Underfilling: difference between revisions
Diff·revision 14 → 15·03:40, 22 May 2025
Difference between revision 14 and revision 15 of Underfilling. 2 lines changed; the page grew by 431 bytes.
| Revision 14 — 01:17, 5 May 2025 SelectTrialSam (talk) split §What a report shows from §What it does not 3,432 bytes ±0 | Revision 15 — 03:40, 22 May 2025 StubSorterBot (talk) bot: sort category members 3,863 bytes +431 | ||
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| 33 | The arithmetic that matters is straightforward. A vial containing 5.0 mg of solid at 80% peptide content contains 4.0 mg of peptide, whatever its purity figure says; the same vial at 60% content contains 3.0 mg. Content in the 70–90% range is ordinary for a [[Trifluoroacetate counterion|trifluoroacetate-salted]] lyophilisate, and figures below that are not rare.{{r|usp1503}} | 33 | The arithmetic that matters is straightforward. A vial containing 5.0 mg of solid at 80% peptide content contains 4.0 mg of peptide, whatever its purity figure says; the same vial at 60% content contains 3.0 mg. Content in the 70–90% range is ordinary for a [[Trifluoroacetate counterion|trifluoroacetate-salted]] lyophilisate, and figures below that are not rare.{{r|usp1503}} |
| 34 | 34 | ||
| + | 35 | Gravimetry is accessible outside a laboratory. Weighing a sealed vial against an empty vial of the same type gives an approximate fill mass; the approximation is limited by variation in the glass and closure, which for small fills can be comparable with the fill itself. Weighing several units of the same type reduces that error and also reveals vial-to-vial spread, which is often the more informative observation.{{r|reports}} | |
| + | 36 | ||
| 35 | == References == | 37 | == References == |
| 36 | {{reflist}} | 38 | {{reflist}} |