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Talk:Bacterial endotoxin test

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This is the discussion page for the article Bacterial endotoxin test. It is for improving the article: sources, wording, structure, scope and titles. It is not a general discussion forum about the subject, and it is not a place to ask for advice — see Project:Medical disclaimer.

Sterile but pyrogenicResolved

"A preparation can be sterile and pyrogenic at the same time" belongs in the lead, not buried. It is the single fact that explains why two separate tests exist. EndotoxinEd (talk) 09:30, 23 January 2026 (UTC)

Moved to the second paragraph of the lead. ✓ Done Chromatokid (talk) 13:05, 23 January 2026 (UTC)

Resolved. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.

Recombinant factor CDone

Worth noting the β-glucan point — the crab lysate responds to glucans as well as endotoxin, which is a source of false positives that rFC avoids. NewLabNell (talk) 10:45, 6 April 2026 (UTC)

Added. It is also the practical reason some laboratories have moved, aside from the animal-welfare argument. ✓ Done EndotoxinEd (talk) 14:20, 6 April 2026 (UTC)

Done. This thread is closed. Reopening it is fine if new sources appear; please add a new subsection rather than editing the closed discussion.

Absence of the determination

Good that the article says the absence of an endotoxin figure is not evidence of a problem. Research material is not a parenteral product and is not held to that standard. BalanceBirdie (talk) 11:35, 11 June 2026 (UTC)

And equally that its presence does not make the material suitable for any particular use. Both halves are needed. DisclosureDido (talk) 15:00, 11 June 2026 (UTC)

This page was last edited on 11 June 2026, by DisclosureDido. Text is available under the PeptidePedia Wiki Content Licence (PPCL-BY-SA 4.0).