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Syringe dead space: difference between revisions

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Revision 44 — 11:27, 16 Feb 2026
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137Community-collated measurements of devices commonly used with reconstituted research peptides exist but are self-reported, use domestic balances of unstated calibration status, and do not control for the protocol variables above. They are consistent with the published device classes in magnitude and are not adequate to support finer distinctions.{{r|ppdeadspace}}137Community-collated measurements of devices commonly used with reconstituted research peptides exist but are self-reported, use domestic balances of unstated calibration status, and do not control for the protocol variables above. They are consistent with the published device classes in magnitude and are not adequate to support finer distinctions.{{r|ppdeadspace}}
138138
+139== Terminology and reporting problems ==
+140Three recurring problems make the topic harder to read about than its physics warrants.
+141
+142The first is the conflation described above: a dead-space volume is quoted as though it were automatically a dose error. It is only a dose error under a specific condition — gas occupying the dead space when the dose is measured — and the condition is often left implicit.
+143
139== References ==144== References ==
140{{reflist}}145{{reflist}}
153* World Health Organization and UNAIDS. ''Technical Brief: Low Dead Space Syringes'' — the public-health framing of the parameter.158* World Health Organization and UNAIDS. ''Technical Brief: Low Dead Space Syringes'' — the public-health framing of the parameter.
154* Frid AH, Kreugel G, Grassi G, et al. "New insulin delivery recommendations." ''Mayo Clinic Proceedings'' 91(9):1231–1255 (2016) — needle length and technique, with dead space treated in passing.159* Frid AH, Kreugel G, Grassi G, et al. "New insulin delivery recommendations." ''Mayo Clinic Proceedings'' 91(9):1231–1255 (2016) — needle length and technique, with dead space treated in passing.
+160
+161== External links ==
+162* [https://www.iso.org/ ISO 7886 series (catalogue entry)] — Device standards for single-use hypodermic syringes. Paywalled.
155163
156== See also ==164== See also ==