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Sterility testing: difference between revisions

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Revision 3 — 14:08, 4 Oct 2024
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add the plate-count expression and define its terms
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Revision 4 — 02:34, 23 Oct 2024
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16Two media are used in parallel: a soybean–casein digest medium incubated at 20–25 °C for fungi and aerobic organisms, and a fluid thioglycollate medium at 30–35 °C for anaerobes and aerobes. Incubation is for not less than fourteen days, which is why a sterility result is never available quickly.16Two media are used in parallel: a soybean–casein digest medium incubated at 20–25 °C for fungi and aerobic organisms, and a fluid thioglycollate medium at 30–35 °C for anaerobes and aerobes. Incubation is for not less than fourteen days, which is why a sterility result is never available quickly.
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+18Method suitability must be demonstrated before the test means anything. The sample must be shown not to inhibit growth of specified challenge organisms in the media used; a sample with antimicrobial activity that has not been neutralised will pass the test by suppressing the growth it is meant to reveal.{{r|usp71}}
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18== References ==20== References ==
19{{reflist}}21{{reflist}}