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Number needed to treat: difference between revisions

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35It also assumes a binary outcome. For a continuous endpoint such as weight change, a number needed to treat requires a threshold — for example, the number needed to treat for one additional person to lose 10% of body weight — and the choice of threshold changes the number.{{r|altman1998}} Where the threshold is not pre-specified, the resulting figure is a post hoc construction.{{r|ich_e9}}35It also assumes a binary outcome. For a continuous endpoint such as weight change, a number needed to treat requires a threshold — for example, the number needed to treat for one additional person to lose 10% of body weight — and the choice of threshold changes the number.{{r|altman1998}} Where the threshold is not pre-specified, the resulting figure is a post hoc construction.{{r|ich_e9}}
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+37Finally, it says nothing about the size of the benefit to the person who benefits. Two treatments with identical numbers needed to treat may prevent a transient symptom and a fatal event respectively.{{r|laupacis1988}}
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37== References ==39== References ==
38{{reflist}}40{{reflist}}