Loss on drying: difference between revisions
Diff·revision 6 → 7·08:45, 24 Oct 2024
Difference between revision 6 and revision 7 of Loss on drying. 2 lines changed; the page grew by 295 bytes.
| Revision 6 — 06:56, 6 Oct 2024 PancreasPru (talk) split §Principle from §Practical limitations 2,274 bytes +37 | Revision 7 — 08:45, 24 Oct 2024 LOD_Lorcan (talk) add the note on co-elution and what it hides 2,569 bytes +295 | ||
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| 18 | The conditions are part of the result. Drying at 105 °C removes more than drying at 60 °C; drying under vacuum removes more than at atmospheric pressure. A figure quoted without its conditions is not comparable with another figure quoted without its conditions. | 18 | The conditions are part of the result. Drying at 105 °C removes more than drying at 60 °C; drying under vacuum removes more than at atmospheric pressure. A figure quoted without its conditions is not comparable with another figure quoted without its conditions. |
| 19 | 19 | ||
| + | 20 | For peptides the conditions must be gentle enough to avoid decomposition. Aggressive drying can cause loss of mass through degradation rather than through evaporation, which inflates the figure and damages the sample; vacuum drying at moderate temperature is the usual compromise.{{r|usp1503}} | |
| + | 21 | ||
| 20 | == References == | 22 | == References == |
| 21 | {{reflist}} | 23 | {{reflist}} |