Glossary of peptide terminology: difference between revisions
Diff·revision 1 → 2·13:59, 21 Jul 2024
Difference between revision 1 and revision 2 of Glossary of peptide terminology. 11 lines changed; the page grew by 1,004 bytes.
| Revision 1 — 16:03, 16 Jul 2024 MolarMassMaeve (talk) start the list; inclusion criterion in the lead 1,029 bytes +1,029 | Revision 2 — 13:59, 21 Jul 2024 ReaderRosalie (talk) expand §Analysis and documentation 2,033 bytes +1,004 | ||
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| 9 | Definitions here are deliberately brief. Where a term carries a distinction that matters — purity against content, sterility against endotoxin freedom, contraindication against warning — the entry states the distinction and the article develops it.{{r|usp621}} | 9 | Definitions here are deliberately brief. Where a term carries a distinction that matters — purity against content, sterility against endotoxin freedom, contraindication against warning — the entry states the distinction and the article develops it.{{r|usp621}} |
| 10 | 10 | ||
| + | 11 | == Chemistry and manufacture == | |
| + | 12 | ; Aib : α-aminoisobutyric acid, a non-proteinogenic residue used to block [[Dipeptidyl peptidase-4|DPP-4]] cleavage. | |
| + | 13 | ; Acylation : Attachment of a fatty acid to a peptide, usually for [[Albumin binding half-life extension|albumin binding]]. | |
| + | 14 | ; Crude : The material obtained directly after [[Resin cleavage|cleavage]], before purification. See [[Crude peptide]]. | |
| + | 15 | ; Deletion sequence : A synthesis by-product missing one or more residues. | |
| + | 16 | ; [[Fmoc chemistry|Fmoc]] : The base-labile temporary protecting group scheme dominating peptide synthesis. | |
| + | 17 | ; Linker : The resin attachment defining the C-terminal functionality of the finished peptide. | |
| + | 18 | ; Lyophilisation : Freeze-drying; the isolation step producing the powder in a vial. See [[Lyophilisation]]. | |
| + | 19 | ; [[Solid-phase peptide synthesis|SPPS]] : Assembly of a peptide on an insoluble support. | |
| + | 20 | ; [[Trifluoroacetate counterion|TFA salt]] : The salt form in which most reverse-phase-purified peptides are isolated.{{r|usp1503}} | |
| + | 21 | ||
| 11 | == References == | 22 | == References == |
| 12 | {{reflist}} | 23 | {{reflist}} |