Cost per milligram: difference between revisions
Diff·revision 10 → 11·02:16, 5 Apr 2025
Difference between revision 10 and revision 11 of Cost per milligram. 12 lines changed; the page grew by 854 bytes.
| Revision 10 — 18:36, 22 Mar 2025 StubTagTeodor (talk) expand §Approved products 2,147 bytes +24 | Revision 11 — 02:16, 5 Apr 2025 TirzTaxonomist (talk) correct the deductible description 3,001 bytes +854 | ||
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| 20 | This is the practical consequence of the purity-versus-content distinction that runs through this wiki. A purity figure normalises away the quantity, and quantity is what a price is paid for.{{r|usp1503}} | 20 | This is the practical consequence of the purity-versus-content distinction that runs through this wiki. A purity figure normalises away the quantity, and quantity is what a price is paid for.{{r|usp1503}} |
| 21 | 21 | ||
| + | 22 | == Other axes that a price hides == | |
| + | 23 | | Factor | Effect on a per-milligram comparison | | |
| + | 24 | |---|---| | |
| + | 25 | | [[Peptide content]] and water | Direct; often 15–30% | | |
| + | 26 | | Fill accuracy | Direct; see [[Underfilling]] | | |
| + | 27 | | Documentation supplied | Not in the price | | |
| + | 28 | | Shipping and cold chain | Sometimes separate | | |
| + | 29 | | Minimum order quantity | Changes effective unit price | | |
| + | 30 | ||
| + | 31 | Documentation is the axis most often invisible. A certificate reporting identity, purity, content, water and counterion costs the supplier something to produce, and material supplied with it is not the same product as material supplied without.{{r|reports}} The records behind such a document cost something to maintain as well.{{r|ich_q7}} | |
| + | 32 | ||
| 22 | == References == | 33 | == References == |
| 23 | {{reflist}} | 34 | {{reflist}} |
| 24 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> | 35 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> |
| 25 | <ref name="reports">PeptidePedia Wiki community test-report tally, 2024–2026 (self-reported; see [[Project:Sourcing_guidelines]]).</ref> | 36 | <ref name="reports">PeptidePedia Wiki community test-report tally, 2024–2026 (self-reported; see [[Project:Sourcing_guidelines]]).</ref> |
| + | 37 | <ref name="ich_q7">International Council for Harmonisation, ''Q7: Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients'' (2000).</ref> | |
| 26 | 38 | ||
| 27 | {{DEFAULTSORT:Cost per milligram}} | 39 | {{DEFAULTSORT:Cost per milligram}} |