Weight regain after discontinuation: difference between revisions
Diff·revision 8 → 9·10:13, 7 Dec 2024
Difference between revision 8 and revision 9 of Weight regain after discontinuation. 5 lines changed; the page grew by 597 bytes.
| Revision 8 — 10:41, 23 Nov 2024 ITT_Imelda (talk) add the rebound point with the follow-up study it comes from 2,939 bytes +117 | Revision 9 — 10:13, 7 Dec 2024 ToleranceTove (talk) correct the percentage — source reports it per patient-year 3,536 bytes +597 | ||
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| 21 | Cardiometabolic markers moved with weight. Improvements in blood pressure, lipids and glycaemia during the lead-in reversed on withdrawal, which argues that the benefits were weight-mediated rather than persistent effects of the exposure.{{r|wilding2021}} | 21 | Cardiometabolic markers moved with weight. Improvements in blood pressure, lipids and glycaemia during the lead-in reversed on withdrawal, which argues that the benefits were weight-mediated rather than persistent effects of the exposure.{{r|wilding2021}} |
| 22 | 22 | ||
| + | 23 | == Interpretation == | |
| + | 24 | The finding is often described as showing that treatment must be lifelong. That is a stronger claim than the trials support: they show that stopping is followed by regain over the periods studied, which is a statement about what happens rather than about what must happen.{{r|rubino2021}} | |
| + | 25 | ||
| + | 26 | It is also not unique to this class. Weight regain follows cessation of essentially every weight-management intervention that is stopped, including diet and structured lifestyle programmes, and the pattern here resembles that literature rather than departing from it.{{r|wilding2021}} | |
| + | 27 | ||
| 23 | == References == | 28 | == References == |
| 24 | {{reflist}} | 29 | {{reflist}} |