Trial data comparison: difference between revisions
Diff·revision 28 → 29·14:12, 29 Apr 2025
Difference between revision 28 and revision 29 of Trial data comparison. 7 lines changed; the page grew by 332 bytes.
| Revision 28 — 10:59, 21 Apr 2025 LiraLotte (talk) rm unsourced claim per PP:V 4,023 bytes ±0 | Revision 29 — 14:12, 29 Apr 2025 ColumnOvenCoy (talk) label community tally as self-reported 4,355 bytes +332 | ||
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| 33 | The gap between them is not small. In the STEP programme the two estimands for the same trial differed by roughly one to two percentage points of body weight, which is a difference of the same order as the gap between some of the drugs being compared.{{r|step1}} A table that mixes estimands between rows therefore manufactures apparent differences between compounds that are artefacts of the analysis choice. | 33 | The gap between them is not small. In the STEP programme the two estimands for the same trial differed by roughly one to two percentage points of body weight, which is a difference of the same order as the gap between some of the drugs being compared.{{r|step1}} A table that mixes estimands between rows therefore manufactures apparent differences between compounds that are artefacts of the analysis choice. |
| 34 | 34 | ||
| + | 35 | |+ The same trial under two estimands | |
| + | 36 | | Estimand | Question answered | Effect on the figure | | |
| + | 37 | |---|---|---| | |
| + | 38 | | Treatment policy | What prescribing achieves | Smaller; includes discontinuations | | |
| + | 39 | | Trial product | What the molecule does on treatment | Larger; censors discontinuation | | |
| + | 40 | | Not stated | — | Unusable for comparison | | |
| + | 41 | ||
| 35 | == References == | 42 | == References == |
| 36 | {{reflist}} | 43 | {{reflist}} |