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Sarcopenia (revision 3)

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Sarcopenia
Defined byLow muscle strength, confirmed by low muscle quantity
Assessed byGrip strength, chair-stand time, gait speed
Not defined byMuscle mass alone
Topic infobox · conventions

Sarcopenia is the loss of skeletal muscle accompanied by loss of strength or physical performance. Current consensus definitions place low muscle strength as the primary criterion, with low muscle quantity as confirmation — a deliberate reversal of earlier mass-based definitions.[1]

The reordering matters for how the topic is discussed in the context of weight reduction. A fall in lean mass measured by body composition assessment is not sarcopenia; a fall in strength or function is the finding that would be.[1]

Definition and assessment

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Consensus definitions require low muscle strength for a probable diagnosis, confirmed by low muscle quantity or quality, with poor physical performance indicating severity.[1]

DomainCommon measures
StrengthGrip strength; chair-stand time
QuantityAppendicular lean mass by DXA
PerformanceGait speed; short physical performance battery

References

  1. ^ a b c Cruz-Jentoft AJ, Bahat G, Bauer J, et al. "Sarcopenia: revised European consensus on definition and diagnosis." Age and Ageing 48(1):16–31 (2019). DOI:10.1093/ageing/afy169. PMID 30312372.