Reference standard (revision 1)
Old revision·17:49, 6 Jul 2024·EndpointEnid
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| Reference standard | |
|---|---|
| Primary standard | Characterised without reference to another standard |
| Secondary standard | Qualified against a primary standard |
| Carries | Assigned content, identity data, expiry, storage conditions |
| Topic infobox · conventions | |
A reference standard is a material of established identity and assigned content used to calibrate an analytical method. Without one, a chromatographic determination yields a normalised proportion — area percent — but not a quantity, and a retention time yields a comparison but not an identification.[1]
Standards are described as primary or secondary. A primary standard is characterised by absolute methods without reference to another standard of the same substance; a secondary standard is qualified against a primary one and is what most laboratories actually use. Pharmacopoeial standards are the archetype of the first category.[1]
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