Reconstitution of lyophilised peptides: difference between revisions
Diff·revision 10 → 11·02:23, 8 Oct 2024
Difference between revision 10 and revision 11 of Reconstitution of lyophilised peptides. 1 line changed; the page grew by 129 bytes.
| Revision 10 — 07:01, 29 Sep 2024 LyophilLena (talk) correct the label on the second column — that is volume, not mass 2,961 bytes ±0 | Revision 11 — 02:23, 8 Oct 2024 CategoryBot (talk) bot: add stub category 3,090 bytes +129 | ||
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| 7 | | Consequence = Solution stability is far shorter than powder stability | 7 | | Consequence = Solution stability is far shorter than powder stability |
| 8 | }} | 8 | }} |
| + | 9 | {{hatnote|For the calculator, see [[Reconstitution calculator]]. For the drying process this reverses, see [[Lyophilisation]].}} | |
| 9 | 10 | ||
| 10 | '''Reconstitution''' is the dissolution of a [[Lyophilisation|lyophilised]] peptide cake in a liquid diluent. The dried solid is the stable form: once in solution the peptide is exposed to hydrolysis, [[Deamidation|deamidation]], oxidation and [[Peptide aggregation|aggregation]], all of which proceed far faster in the liquid phase.{{r|manning2010}} | 11 | '''Reconstitution''' is the dissolution of a [[Lyophilisation|lyophilised]] peptide cake in a liquid diluent. The dried solid is the stable form: once in solution the peptide is exposed to hydrolysis, [[Deamidation|deamidation]], oxidation and [[Peptide aggregation|aggregation]], all of which proceed far faster in the liquid phase.{{r|manning2010}} |