Placebo-adjusted effect: difference between revisions
Diff·revision 11 → 12·12:32, 4 Apr 2025
Difference between revision 11 and revision 12 of Placebo-adjusted effect. 2 lines changed; the page grew by 222 bytes.
| Revision 11 — 13:25, 18 Mar 2025 GramsNotUnitsGil (talk) attribute the subgroup finding as exploratory 3,671 bytes ±0 | Revision 12 — 12:32, 4 Apr 2025 AxisLabelAgda (talk) state the non-inferiority margin, since the design was non-inferiority 3,893 bytes +222 | ||
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| 30 | The third row deserves attention: a ratio between arms is unstable when the placebo change is near zero, and a trial with a placebo change of −0.5% will produce a spectacular ratio from an unremarkable difference.{{r|ich_e9}} | 30 | The third row deserves attention: a ratio between arms is unstable when the placebo change is near zero, and a trial with a placebo change of −0.5% will produce a spectacular ratio from an unremarkable difference.{{r|ich_e9}} |
| 31 | 31 | ||
| + | 32 | Cross-trial comparison compounds all of this. Two trials with different lifestyle interventions have different placebo arms, so their active-arm figures are not comparable even when the drug effects are.{{r|wilding2021}} | |
| + | 33 | ||
| 32 | == References == | 34 | == References == |
| 33 | {{reflist}} | 35 | {{reflist}} |