Peptide content: difference between revisions
Diff·revision 9 → 10·20:39, 26 Dec 2024
Difference between revision 9 and revision 10 of Peptide content. 2 lines changed; the page grew by 142 bytes.
| Revision 9 — 12:04, 10 Dec 2024 IsocraticIla (talk) rm the assertion that two laboratories must agree; they need not 3,952 bytes ±0 | Revision 10 — 20:39, 26 Dec 2024 LipidLedgerLou (talk) fix a dangling clause 4,094 bytes +142 | ||
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| 1 | {{Infobox method | 1 | {{Infobox method |
| 2 | | name = Peptide content | 2 | | name = Peptide content |
| + | 3 | | subtitle = Mass fraction | |
| 3 | | image = titration.svg | 4 | | image = titration.svg |
| 4 | | caption = Content is a mass balance: what is in the vial that is not peptide has to be measured before what is can be stated. | 5 | | caption = Content is a mass balance: what is in the vial that is not peptide has to be measured before what is can be stated. |
| ⋮ | ⋮ | ||
| 8 | | Typical range = 70–90% for a lyophilised trifluoroacetate salt | 9 | | Typical range = 70–90% for a lyophilised trifluoroacetate salt |
| 9 | }} | 10 | }} |
| + | 11 | {{hatnote|For the relative chromatographic measure usually reported as "purity", see [[Area percent purity]].}} | |
| 10 | 12 | ||
| 11 | '''Peptide content''', sometimes called peptide net content, is the proportion of the mass of a preparation that is the peptide itself. Everything else in the vial — water taken up during and after [[Lyophilisation|lyophilisation]], the counterion left by the purification step, residual solvent, and any excipient — is excluded from the numerator and included in the denominator.{{r|usp1503}} | 13 | '''Peptide content''', sometimes called peptide net content, is the proportion of the mass of a preparation that is the peptide itself. Everything else in the vial — water taken up during and after [[Lyophilisation|lyophilisation]], the counterion left by the purification step, residual solvent, and any excipient — is excluded from the numerator and included in the denominator.{{r|usp1503}} |