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Methionine oxidation: difference between revisions

Diff·revision 10 → 11·16:14, 24 Apr 2025

Difference between revision 10 and revision 11 of Methionine oxidation. 2 lines changed; the page grew by 268 bytes.

Revision 10 — 05:27, 25 Mar 2025
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Revision 11 — 16:14, 24 Apr 2025
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add the ionisation mode to the mass-spectrometry description
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25Chromatographically the sulfoxide is more polar than the parent and elutes earlier on [[Reverse-phase HPLC|reverse phase]], usually with adequate resolution. It therefore appears as a distinct related substance on a competent method and is included in an itemised related-substances table; resolving it from the parent is part of what a specificity assessment demonstrates.{{r|ich_q2}}25Chromatographically the sulfoxide is more polar than the parent and elutes earlier on [[Reverse-phase HPLC|reverse phase]], usually with adequate resolution. It therefore appears as a distinct related substance on a competent method and is included in an itemised related-substances table; resolving it from the parent is part of what a specificity assessment demonstrates.{{r|ich_q2}}
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+27Control strategies are the ordinary ones: exclude oxygen from the headspace, protect from light, avoid metal contact, keep the material cold and dry. Antioxidants are used in formulated products but are not present in unformulated research material.{{r|manning2010}}
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27== References ==29== References ==
28{{reflist}}30{{reflist}}