Melanotan II (revision 1)
Old revision·09:00, 19 Nov 2024·ITT_Imelda
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| Melanotan II | |
|---|---|
| Class | Melanocortin receptor agonist |
| Selectivity | Non-selective across MC1R, MC3R, MC4R, MC5R |
| Status | Not approved in any jurisdiction |
| Related approved compound | Bremelanotide (MC4R-directed) |
| Compound infobox · conventions | |
Melanotan II is a synthetic cyclic analogue of α-melanocyte-stimulating hormone and a non-selective agonist at melanocortin receptors. It is not approved in any jurisdiction and is distributed as a research chemical.[1]
Non-selectivity is the defining property. Agonism at MC1R produces melanogenesis, the effect for which it is sought; agonism at MC4R affects appetite and sexual function; agonism at MC3R and MC5R contributes further effects. A single compound producing all of them simultaneously is a pharmacological blunt instrument.[1]
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