Melanotan II: difference between revisions
Diff·revision 16 → 17·17:13, 5 Aug 2025
Difference between revision 16 and revision 17 of Melanotan II. 6 lines changed; the page grew by 650 bytes.
| Revision 16 — 09:55, 18 Jul 2025 GHK_Gwendolen (talk) rm the bodybuilding-forum citation per PP:V 3,724 bytes ±0 | Revision 17 — 17:13, 5 Aug 2025 ArcuateArt (talk) British spelling per PP:MOS 4,374 bytes +650 | ||
|---|---|---|---|
| 29 | The honest position is that a mechanistic reason for concern exists — melanocyte stimulation — the case reports exist, and causation is not demonstrated.{{r|cardones2009}} | 29 | The honest position is that a mechanistic reason for concern exists — melanocyte stimulation — the case reports exist, and causation is not demonstrated.{{r|cardones2009}} |
| 30 | 30 | ||
| + | 31 | == Status == | |
| + | 32 | Melanotan II is not approved anywhere and several regulators have issued warnings about products sold under the name. It is prohibited in competitive sport.{{r|hadley2005}} | |
| + | 33 | ||
| + | 34 | Material sold as melanotan II is subject to the same documentary considerations as any research peptide. It is a short cyclic peptide and therefore a simpler synthesis than the incretin analogues, though cyclisation adds its own impurity possibilities. See [[Certificate of analysis]] and [[Peptide content]].{{r|usp1503}} | |
| + | 35 | ||
| 31 | == References == | 36 | == References == |
| 32 | {{reflist}} | 37 | {{reflist}} |
| ⋮ | ⋮ | ||
| 34 | <ref name="cardones2009">Cardones AR, Grichnik JM. "α-Melanocyte-stimulating hormone-induced eruptive nevi." ''Archives of Dermatology'' 145(4):441–444 (2009). PMID 19380667.</ref> | 39 | <ref name="cardones2009">Cardones AR, Grichnik JM. "α-Melanocyte-stimulating hormone-induced eruptive nevi." ''Archives of Dermatology'' 145(4):441–444 (2009). PMID 19380667.</ref> |
| 35 | <ref name="cone2005">Cone RD. "Anatomy and regulation of the central melanocortin system." ''Nature Neuroscience'' 8(5):571–578 (2005). PMID 15856065.</ref> | 40 | <ref name="cone2005">Cone RD. "Anatomy and regulation of the central melanocortin system." ''Nature Neuroscience'' 8(5):571–578 (2005). PMID 15856065.</ref> |
| + | 41 | <ref name="usp1503">United States Pharmacopeia, General Chapter <1503>, ''Quality Attributes of Synthetic Peptide Drug Substances''.</ref> | |
| 36 | 42 | ||
| 37 | == See also == | 43 | == See also == |