Loss on drying: difference between revisions
Diff·revision 13 → 14·03:05, 24 Feb 2025
Difference between revision 13 and revision 14 of Loss on drying. 2 lines changed; the page grew by 397 bytes.
| Revision 13 — 23:03, 1 Feb 2025 HOMA_Hettie (talk) expand §Why the distinction from water matters 3,338 bytes ±0 | Revision 14 — 03:05, 24 Feb 2025 KarlFischerKit (talk) expand §Why the distinction from water matters 3,735 bytes +397 | ||
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| 31 | | Counterion assay | [[Trifluoroacetate counterion]] or acetate content | | 31 | | Counterion assay | [[Trifluoroacetate counterion]] or acetate content | |
| 32 | 32 | ||
| + | 33 | A certificate reporting loss on drying ''and'' residual solvents separately is at risk of double counting if both are subtracted, since the solvent contributed to the drying loss. A certificate reporting Karl Fischer water and residual solvents separately is not. This is the practical reason the compendial guidance on peptide quality attributes prefers the specific determinations.{{r|usp921}} | |
| + | 34 | ||
| 33 | == References == | 35 | == References == |
| 34 | {{reflist}} | 36 | {{reflist}} |