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Incretin effect: difference between revisions

Diff·revision 39 → 40·22:06, 27 Mar 2025

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Revision 39 — 12:57, 19 Mar 2025
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Revision 40 — 22:06, 27 Mar 2025
ExenatideEzra (talk)
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31where {{math|I_{\text{oral}}}} is the integrated insulin secretion over 2–3 hours following oral glucose, and {{math|I_{\text{iv}}}} is that following intravenous glucose at matched glucose kinetics.{{r|nauck2018}}31where {{math|I_{\text{oral}}}} is the integrated insulin secretion over 2–3 hours following oral glucose, and {{math|I_{\text{iv}}}} is that following intravenous glucose at matched glucose kinetics.{{r|nauck2018}}
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+33Measurement requires both an oral glucose-tolerance test and a euglycaemic-hyperglycaemic clamp on separate days. Because the clamp is labour-intensive and requires careful blood sampling, the incretin effect is not routinely measured in clinical practice; it is a research tool for mechanistic investigations and for assessing drug effects.
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33== References ==35== References ==
34{{reflist}}36{{reflist}}