Growth hormone secretagogue (revision 1)
Old revision·21:38, 25 Oct 2024·SPPS_Sorrel
This is an old revision of this page, as it stood at 21:38, 25 Oct 2024, saved by SPPS_Sorrel with the summary new article: research peptide, expansion welcome. It may differ substantially from the current revision, and any error it contains may since have been corrected.
| Growth hormone secretagogue | |
|---|---|
| Two receptor families | GHRH receptor; ghrelin receptor (GHS-R1a) |
| GHRH analogues | Sermorelin, CJC-1295, Tesamorelin |
| Ghrelin-receptor agonists | Ipamorelin, and related compounds |
| Approved example | Tesamorelin, for a specific indication |
| Topic infobox · conventions | |
Growth hormone secretagogues are compounds that stimulate release of endogenous growth hormone, in contrast to administration of growth hormone itself. Two receptor families are involved: the receptor for growth hormone-releasing hormone, and the ghrelin receptor GHS-R1a.[1]
GHRH analogues — sermorelin, CJC-1295, tesamorelin — mimic the hypothalamic releasing hormone. Ghrelin-receptor agonists such as ipamorelin act at a separate receptor and by a partly complementary mechanism.[1]