Glucagon-like peptide-1: difference between revisions
Diff·revision 18 → 19·02:13, 2 Sep 2024
Difference between revision 18 and revision 19 of Glucagon-like peptide-1. 9 lines changed; the page grew by 397 bytes.
| Revision 18 — 02:12, 27 Aug 2024 ForestPlotFinn (talk) move table to the section it supports 5,430 bytes ±0 | Revision 19 — 02:13, 2 Sep 2024 TrialsTabitha (talk) rm citation to a supplier's own page 5,827 bytes +397 | ||
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| 31 | L cells are open-type epithelial cells whose apical surface contacts the lumen, giving them direct access to nutrient stimuli. Secretion is biphasic: an early rise within 10–15 minutes of ingestion, attributed partly to neural and endocrine relay from the proximal gut, followed by a later phase as nutrients reach the ileum and colon.{{r|holst2007}} | 31 | L cells are open-type epithelial cells whose apical surface contacts the lumen, giving them direct access to nutrient stimuli. Secretion is biphasic: an early rise within 10–15 minutes of ingestion, attributed partly to neural and endocrine relay from the proximal gut, followed by a later phase as nutrients reach the ileum and colon.{{r|holst2007}} |
| 32 | 32 | ||
| + | 33 | | Stimulus class | Examples | Relative potency | | |
| + | 34 | |---|---|---| | |
| + | 35 | | Carbohydrate | Glucose, sucrose | Moderate | | |
| + | 36 | | Lipid | Long-chain fatty acids, monoacylglycerols | High | | |
| + | 37 | | Protein | Peptones, specific amino acids | Moderate to high | | |
| + | 38 | | Bile acids | Deoxycholate via TGR5 | Moderate | | |
| + | 39 | | Short-chain fatty acids | Products of colonic fermentation | Low to moderate | | |
| + | 40 | ||
| 33 | == References == | 41 | == References == |
| 34 | {{reflist}} | 42 | {{reflist}} |
| ⋮ | ⋮ | ||
| 45 | [[Category:Peptide drugs]] | 53 | [[Category:Peptide drugs]] |
| 46 | [[Category:Appetite regulation]] | 54 | [[Category:Appetite regulation]] |
| + | 55 | [[Category:Pharmacokinetics]] | |
| 47 | 56 |