Glossary of peptide terminology (revision 4)

This glossary defines terms used across PeptidePedia Wiki. Each entry gives a short definition and, where a full article exists, links to it. Terms are grouped by domain and ordered alphabetically within each group.^[1]

Definitions here are deliberately brief. Where a term carries a distinction that matters — purity against content, sterility against endotoxin freedom, contraindication against warning — the entry states the distinction and the article develops it.^[2]

The glossary is not a substitute for the articles and does not attempt completeness.^[3]

Aib

α-aminoisobutyric acid, a non-proteinogenic residue used to block DPP-4 cleavage.

Acylation

Attachment of a fatty acid to a peptide, usually for albumin binding.

Crude

The material obtained directly after cleavage, before purification. See Crude peptide.

Deletion sequence

A synthesis by-product missing one or more residues.

Fmoc

The base-labile temporary protecting group scheme dominating peptide synthesis.

Linker

The resin attachment defining the C-terminal functionality of the finished peptide.

Lyophilisation

Freeze-drying; the isolation step producing the powder in a vial. See Lyophilisation.

SPPS

Assembly of a peptide on an insoluble support.

TFA salt

The salt form in which most reverse-phase-purified peptides are isolated.^[1]