GLP-1 receptor: difference between revisions
Diff·revision 6 → 7·17:16, 15 Aug 2024
Difference between revision 6 and revision 7 of GLP-1 receptor. 5 lines changed; the page grew by 239 bytes.
| Revision 6 — 19:30, 4 Aug 2024 ReaderRosalie (talk) de-duplicate a repeated sentence 3,475 bytes +350 | Revision 7 — 17:16, 15 Aug 2024 CustomsClarke (talk) attribute the gastric-emptying effect to the study that measured it 3,714 bytes +239 | ||
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| 4 | | Family = Class B1 secretin-like GPCR | 4 | | Family = Class B1 secretin-like GPCR |
| 5 | | Endogenous ligand = [[Glucagon-like peptide-1]] | 5 | | Endogenous ligand = [[Glucagon-like peptide-1]] |
| + | 6 | <!-- Signalling --> | |
| + | 7 | | Principal coupling = G<sub>s</sub> → adenylyl cyclase → cAMP | |
| + | 8 | | Secondary = G<sub>q</sub>, β-arrestin recruitment | |
| + | 9 | | Desensitisation = GRK phosphorylation, internalisation | |
| 6 | }} | 10 | }} |
| 7 | 11 | ||
| ⋮ | ⋮ | ||
| 28 | [[Category:Receptor pharmacology]] | 32 | [[Category:Receptor pharmacology]] |
| 29 | [[Category:Incretin biology]] | 33 | [[Category:Incretin biology]] |
| + | 34 | [[Category:Compounds and pharmacology]] | |
| 30 | 35 |