GLP-1 receptor: difference between revisions
Diff·revision 21 → 22·18:55, 7 Jun 2025
Difference between revision 21 and revision 22 of GLP-1 receptor. 3 lines changed; the page grew by 361 bytes.
| Revision 21 — 13:15, 11 May 2025 ExenatideEzra (talk) convert a hard-coded date to the house format 6,670 bytes +252 | Revision 22 — 18:55, 7 Jun 2025 SatietySunniva (talk) ce per PP:MOS 7,031 bytes +361 | ||
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| 53 | The modest resting heart-rate increase of two to four beats per minute reported across the class is attributed to direct action at the sinoatrial node. It has not been associated with adverse outcomes in the completed outcome trials.{{r|drucker2018}} | 53 | The modest resting heart-rate increase of two to four beats per minute reported across the class is attributed to direct action at the sinoatrial node. It has not been associated with adverse outcomes in the completed outcome trials.{{r|drucker2018}} |
| 54 | 54 | ||
| + | 55 | == Genetic variation == | |
| + | 56 | Common coding variants of GLP1R have been associated in genome-wide studies with small differences in fasting glucose and in insulin response to oral glucose. The effect sizes are small relative to the pharmacological effect of an agonist, and no variant has been shown to be useful for predicting response to treatment.{{r|zhang2017}} | |
| + | 57 | ||
| 55 | == References == | 58 | == References == |
| 56 | {{reflist}} | 59 | {{reflist}} |