Counterfeit peptide (revision 3)
Old revision·02:51, 10 Dec 2024·VerifyFirstVida
This is an old revision of this page, as it stood at 02:51, 10 Dec 2024, saved by VerifyFirstVida with the summary clarify that a certificate is a claim by its issuer. It may differ substantially from the current revision, and any error it contains may since have been corrected.
| Counterfeit peptide | |
|---|---|
| Substitution | A different, usually cheaper, compound |
| Dilution | The correct compound with undeclared bulking agent |
| Misrepresented origin | Correct compound, false provenance |
| Detected by | Identity determination, not purity |
| Topic infobox · conventions | |
A counterfeit peptide is material misrepresented as to what it is or where it came from. Three forms are usually distinguished: substitution of a different compound, dilution of the correct compound with an undeclared bulking agent, and misrepresentation of origin where the compound is correct but the stated source is not.[1]
The determination that detects substitution is identity — mass confirmation, and where available sequence confirmation — not purity. A substituted compound analysed alone will return an excellent area percent figure, because it is a pure sample of whatever it actually is.[2]
References
- ^ PeptidePedia Wiki community test-report tally, 2024–2026 (self-reported; see Project:Sourcing guidelines).
- ^ United States Pharmacopeia, General Chapter <1503>, Quality Attributes of Synthetic Peptide Drug Substances.
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